In this research article, the ANN approach was applied to analyze TFR in Honduras. The employed annual data covers the period 1960-2018 and the out-of-sample period ranges over the period 2019-2030. The residuals and forecast evaluation criteria (Error, MSE and MAE) of the applied model indicate that the model is stable in forecasting TFR in Honduras. The results of the study indicate that annual total fertility rates in Honduras are likely to be around 3 births per woman over the out-of-sample period. Therefore, the government of Honduras is encouraged to continue with its current population control policy.